NGAL

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Yunnan Digital-analog Technology Co.,Ltd

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

Description

Neutrophilgelatinase-associated lipocalin (NGAL) is a 25KD glucoprotein and a new member of lipocalin family with a typical β-barrel structure of the family. Based on the recent research, the function of NGAL protein maybe is to protect and regulate the activity of matrix metalloproteinase-9(MMP-9) and to involve in inflammation and innate immunity reaction. NGAL protein also is a novel iron transporter that mediates a new iron delivery pathway. Acute kidney injury(AKI)is a syndrome characterized by loss of function in a short time ( hours to days)The scarcity of early biomarker for AKI has hindered our ability to launch the therapy for this diseaseNeutrophilgelatinase-assocliated lipocalin( NGAL ) is a high efficient clinical biomarker for AKI. At present, Cystatin C is widely used for AKI clinical diagnosis .However, compared to Cystatin C , NGAL diagnosis value for AKI is much higher .

The NGAL provided by our company is the recombinant human proteinwith high immunogenicity. it is not only used to immune animal for producing anti-NGAL antibody, which can be used as the core material for the NGAL diagnosis kit, but also can be used as a quality control standard or positive control test.


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